Feb '18

European Crohn´s and Colitis Organisation (ECCO) Congress

Safety and Immune Modulatory Properties of Etrasimod (APD334), a Next-Generation Oral, Selective Sphingosine 1-Phosphate Receptor Modulator, in Healthy Volunteers

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Apr '17

ASPET 2017 at Experimental Biology (EB)

Etrasimod, a Novel Sphingosine-1-Phosphate Receptor (S1PR1) Modulator, Lacks Functional Activity at S1P2 Receptors
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Etrasimod (APD334), an Oral, Next-Generation Sphingosine-1-Phosphate Receptor Modulator Inhibits the Development of Colitis in Lymphoid-Null Mice Injected with Colitogenic CD4+ T Cells
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Functional Activity of Etrasimod and a Diverse Panel of Sphingosine-1-Phosphate Receptor (S1PR1) Modulators at S1P4 Receptors
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Mar '17

Autoimmunity Reviews

Modulation of sphingosine-1-phosphate in inflammatory bowel disease
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Feb '17

12th Congress of European Crohn’s and Colitis Organisation (ECCO) – Inflammatory Bowel Diseases 2017

Safety, tolerability and lymphocyte-lowering properties of etrasimod (APD334), an oral, potent, next-generation, selective S1P receptor modulator, after dose escalation in healthy volunteers
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DOP077 Immunomodulatory Effects of Etrasimod APD334 an Oral Potent
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DOP078 Pharmacology and Safety of Etrasimod APD334 an Oral Potent
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Dec '16

Advances in Inflammatory Bowel Diseases (AIBD) Meeting

Safety, Pharmacokinetics and Pharmacodynamics of Etrasimod (APD334), an Oral, Selective S1P Receptor Modulator, after Single Dose Escalation in Healthy Volunteers
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Etrasimod (APD334), a Potent, Selective, Oral S1P Receptor Modulator With Preclinical Autoimmune Disease-modifying Activity Exhibits Favorable PK/PD Properties in Healthy Volunteers
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Preclinical Safety Assessment of Etrasimod (APD334), an Oral Sphingosine-1-Phosphate Receptor (S1P) Modulator with a Favorable Profile
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The Sphingosine-1-Phosphate Receptor (S1P) Modulator Etrasimod (APD334) Demonstrates Limited Effects on Heart Rate in Preclinical Testing
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Oct '16

United European Gastroenterology Week (UEGW) Meeting

Abstract 5531 – Receptor Profile and Efficacy of Etrasimod (APD334), an Oral, Next-Generation Sphingosine-1-Phosphate Receptor Modulator in Development for Ulcerative Colitis
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Nov '17

Discovery of APD371

Identification of a Highly Potent and Selective CB2 Agonist for the Treatment of Chronic Pain
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Jan '18

Congress: Pulmonary Vascular Research Institute (PVRI) 12th Annual World Congress on PVD

Efficacy and Safety of the Oral Prostacyclin Receptor (IP) Agonist Ralinepag in Pulmonary Arterial Hypertension (PAH)
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Nov '17

American College of Chest Physicians 2017 Annual Meeting

Arena Pharmaceuticals Announces Late Breaking Presentation of Positive Phase 2 Results with Ralinepag in Patients with Pulmonary Arterial Hypertension
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Sep '17

International Congress of the European Respiratory Society

APD811 ERS 2017 Poster Shen L APD811 (ralinepag), a Novel Non-prostanoid IP Receptor Agonist has Potent Antiproliferative and Vasorelaxant Properties in Human Pulmonary Artery
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APD811 ERS 2017 ePoster Adams J Pharmacokinetics and Efficacy of Ralinepag (APD811) in Rats and Humans
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Aug '17

European Society of Cardiology Congress (ESC) 2017

APD811 (ralinepag), a novel non-prostanoid IP receptor agonist, has potent antiproliferative and vasorelaxant properties in human pulmonary artery
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Comparative receptor pharmacology, pre-clinical efficacy and pharmacokinetics of a novel, next-generation prostacyclin receptor agonist, ralinepag (APD811), in humans and rats
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May '17

American Thoracic Society (ATS) 2017 International Conference

Safety and Pharmacokinetics of Ralinepag (APD811), a Next-generation, Selective Prostacyclin Receptor Agonist, in Healthy Adult Subjects
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Jan '17

Journal of Medicinal Chemistry

Discovery of 2‑(((1r,4r)‑4-(((4-Chlorophenyl)(phenyl)carbamoyl)oxy)methyl)cyclohexyl)methoxy)acetate (Ralinepag): An Orally Active Prostacyclin Receptor Agonist for the Treatment of Pulmonary Arterial Hypertension
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Nov '16

American Heart Association (AHA) Meeting

APD811, a Novel and Highly Selective Non-prostanoid IP Receptor Agonist in Smooth Muscle Cells From Patients With Pulmonary Hypertension
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